Anesthesiologists, in hugely disproportionate numbers compared to other doctors, are getting high.

Before embarking on dangerous rock climbs, Matt Samet would use whiskey to wash down powerful prescription tranquilizers. A first-person account of extreme addiction.

April Savino, a teenage homeless runaway, lived in Grand Central Terminal from 1984 until 1987 when she committed suicide on the steps of a nearby church.

Lenny makes $5,000 a week selling coke. It was easy to get into the business after finishing prep school. Getting out and going legit after his final score is proving much more difficult.

The not-so-underground culture of neuroenhancing drug use, and where it’s headed.

How the actor ended up with a house full of tourniquets and syringes, an unflinching belief in the restorative powers of “ozone,” and the brain scan of someone who has “experienced the equivalent of blunt trauma.”

It took a desperate screenwriter to find Max Mermelstein, Miami’s former coke overlord, after twenty-five years in hiding.

An excerpt from Night of the Gun, the memoir by New York Times media critic David Carr about his years as a junkie in late-‘80s Minneapolis.

From Hong Kong to Bangkok to the Golden Triangle, the author searches for something everyone says no longer exists: an opium den.